The study investigates how intrinsic and extrinsic job satisfaction mediate the relationship between Islamic work ethics (IWE) and organizational citizenship behavior (OCB) among PhD teachers. Using a mixed-method approach, qualitative data were gathered through interviews with 10 PhD teachers from Pakistan and Iran and analyzed with MAXQDA software. This was followed by a quantitative phase where a questionnaire was distributed to 83 PhD scholars, with data analyzed using SMART PLS 4. The findings indicate that Islamic work ethics significantly enhances both types of job satisfaction, which in turn increases OCB. Teachers who view their work as a moral obligation are more likely to engage in behaviors beyond their formal duties. The research suggests that Islamic work ethics creates a work environment where job satisfaction goes beyond financial incentives, fostering commitment among educators. Consequently, this paper recommends that institutions incorporate Islamic work ethics principles into their culture to improve job satisfaction and encourage proactive behaviors among academic staff.